Andreas Knickman, son of cycling great Roy Knickman, Has Cancer

Remember US Cycling Legend Roy Knickman? Recently, his 13 year-old son Andreas was diagnosed with cancer.

“Sep 11, 2009 – NEWBURY PARK, CALIF.–Newbury Park teen Andreas Knickman was diagnosed with bone cancer on July 8, 2009 and immediately underwent surgery to repair his leg and to remove a nodule in his lung. He is now receiving chemotherapy at Children’s Hospital in Los Angeles.”

Roy talks about what it has meant to him and his family over at competetor radio. Thanks to Doucheblog for the head’s up.

You can learn more about Andreas’s current state via CaringBridge.org

Folks interested in making a donation to help the Knickman’s can get more information here, or they should contact Jill Shaffer at 805-480-0309 (e-mail: jshaffer@millerymca.org).

[Editor’s note: yes, a special thanks to Doucheblog for the heads up and for reposting information on this tragic story, which is an unjust companion to the illness of the son of another cycling great who is also a friend of Pappillon.]

Rhabdomyosarcoma – Cancer in Kids – My Friend’s Son Has It (frown)

Much to my dismay, I just found out that the son of a friend and fellow cyclist is suffering from the childhood cancer Rhabdomyosarcoma. My dad died of liver cancer, and my mom survived her own bout with the “C”, so I know the devastation that this disease can cause. To protect his privacy, I won’t publish my friend’s name or that of his son, but if you’d still be willing to send some positive energy to “The Son of the Friend of Joe’s who has Cancer,” it would be greatly appreciated.There’s nothing like Childhood Cancer to make one’s own personal problems seem small by comparison, eh?

[Ed. Pause while readers send positive energy.]

OK! Having sent your positive energy, and with a new perspective on life (thankful for what you have, right?) you now want to know what is Rhabdomyosarcoma? Well, according to the Internet:

Rhabdomyosarcoma is a fast-growing, highly malignant tumor which accounts for over half of the soft tissue sarcomas in children. Less frequently, other soft tissue sarcomas are found in children: fibrosarcoma, mesenchymoma, synovial sarcoma, and liposarcoma.

Rhabdomyosarcoma often causes a noticeable lump on a child’s body. If the tumor is located internally, the symptoms depend on its location. For example, tumors in the nasal passage may put pressure on the eustachian tubes; a bladder tumor can cause trouble urinating; an orbital tumor may cause the eye to protrude.

About Rhabdomyosarcoma

Rhabdomyosarcoma tumors arise from a cell called a “rhabdomyoblast”, which is a primitive muscle cell. Instead of differentiating into striated muscle cells, the rhabdomyoblasts grow out of control. Since this type of muscle is located throughout the body, the tumors can appear at numerous locations. The four major sites in which rhabdomyosarcoma is found are:

* head and neck; around the eyes — 35-40%
* genitourinary tract — 20%
* extremities — 15-20%
* trunk (chest and lungs) — 10-15%

Depending on the “histology” of the cells (how they look under a microscope), the tumors are classified as one of the following:

Embryonal rhabdomyosarcoma. Most common type, usually found in children under 15 and in the head and neck region and genitourinary tract.

Botryoid type. A variant of the embryonal type; the tumor arises as a grape-like lesion in mucosal-lined hollow organs such as the vagina and urinary bladder.

Alveolar type. A more aggressive tumor which usually involves the muscles of the extremities or trunk.

Pleomorphic type. Usually seen in adults and arises in muscles of the extremities.

Embryonal rhabdomyosarcoma is considered the most treatable form of the disease. The prognosis is also affected by the location of the primary tumor. Orbital and genitourinary track rhabdomyosarcomas have a better prognosis than do tumors which originate in the head and neck, extremity, pelvic, and trunk locations.

Prognosis also depends on the stage of the tumor. The Intergroup Rhabdomyosarcoma Study Group has defined a set of guidelines, which assign the tumor to groups 1-4 depending on the extent of the disease. For more information, see the PDQ on the staging of rhabdomyosarcoma.

Treatment

Rhabdomyosarcoma is treated by a combination of surgery, chemotherapy, and radiation.

Surgery. Resection (removal) of the primary tumor. If necessary after chemotherapy or radiation has shrunk the tumor.

Chemotherapy. The following chemotherapy agents are commonly used: vincristine, cyclophosphamide, dactinomycin, adriamycin, ifosfamide, VP-16.

Radiation. External beam radiation is used in some cases of rhabdomyosarcoma.

Statistics

  • Accounts for 5-8% of childhood cancers.
  • 70% of all rhabdomyosarcoma cases diagnosed in the first ten years of life.
  • Usually affects children the ages of 2 to 6 and 15 to 19.
  • The peak incidence in 1-5 age group.
  • Overall, 50% of the children diagnosed with rhabdomyosarcoma survive 5 years.